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Mechanistic study of the solubilization effect of basic amino acids on a poorly water-soluble drug
Amino acids have shown promising abilities to form complexes with poorly water-soluble drugs and improve their physicochemical properties for a better dissolution profile through molecular interactions. Salt formation via ionization between acidic drugs and basic amino acids is known as the major co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240925/ https://www.ncbi.nlm.nih.gov/pubmed/35865577 http://dx.doi.org/10.1039/d2ra02870k |