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A bioinspired carbon monoxide delivery system prevents acute kidney injury and the progression to chronic kidney disease

Renal ischemia-reperfusion (IR)-induced tissue hypoxia causes impaired energy metabolism and oxidative stress. These conditions lead to tubular cell damage, which is a cause of acute kidney injury (AKI) and AKI to chronic kidney disease (CKD). Three key molecules, i.e., hypoxia-inducible factor-1α (...

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Detalles Bibliográficos
Autores principales: Nagasaki, Taisei, Maeda, Hitoshi, Taguchi, Kazuaki, Yanagisawa, Hiroki, Nishida, Kento, Kobayashi, Kazuki, Wada, Naoki, Noguchi, Isamu, Murata, Ryota, Sakai, Hiromi, Kitagishi, Hiroaki, Saruwatari, Junji, Watanabe, Hiroshi, Otagiri, Masaki, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241064/
https://www.ncbi.nlm.nih.gov/pubmed/35763935
http://dx.doi.org/10.1016/j.redox.2022.102371