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A bioinspired carbon monoxide delivery system prevents acute kidney injury and the progression to chronic kidney disease
Renal ischemia-reperfusion (IR)-induced tissue hypoxia causes impaired energy metabolism and oxidative stress. These conditions lead to tubular cell damage, which is a cause of acute kidney injury (AKI) and AKI to chronic kidney disease (CKD). Three key molecules, i.e., hypoxia-inducible factor-1α (...
Autores principales: | Nagasaki, Taisei, Maeda, Hitoshi, Taguchi, Kazuaki, Yanagisawa, Hiroki, Nishida, Kento, Kobayashi, Kazuki, Wada, Naoki, Noguchi, Isamu, Murata, Ryota, Sakai, Hiromi, Kitagishi, Hiroaki, Saruwatari, Junji, Watanabe, Hiroshi, Otagiri, Masaki, Maruyama, Toru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241064/ https://www.ncbi.nlm.nih.gov/pubmed/35763935 http://dx.doi.org/10.1016/j.redox.2022.102371 |
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