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IGDQ motogenic peptide gradient induces directional cell migration through integrin (αv)β3 activation in MDA-MB-231 metastatic breast cancer cells

In the context of breast cancer metastasis study, we have shown in an in vitro model of cell migration that IGDQ-exposing (IsoLeu-Gly-Asp-Glutamine type I Fibronectin motif) monolayers (SAMs) on gold sustain the adhesion of breast cancer MDA-MB-231 cells by triggering Focal Adhesion Kinase and integ...

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Detalles Bibliográficos
Autores principales: Ayama-Canden, Sophie, Tondo, Rodolfo, Piñeros, Liliana, Ninane, Noëlle, Demazy, Catherine, Dieu, Marc, Fattaccioli, Antoine, Tabarrant, Tijani, Lucas, Stéphane, Bonifazi, Davide, Michiels, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241093/
https://www.ncbi.nlm.nih.gov/pubmed/35763908
http://dx.doi.org/10.1016/j.neo.2022.100816