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Farnesoid X receptor protects against cisplatin-induced acute kidney injury by regulating the transcription of ferroptosis-related genes

The side effects of cisplatin, a widely used chemotherapeutic agent, include nephrotoxicity. Previous studies have reported that cisplatin induces ferroptosis and lipid peroxide accumulation. Ferroptosis, a type of regulated cell death, is characterized by iron-dependent lipid peroxidation. Although...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Hyun, Choi, Hoon-In, Park, Jung Sun, Kim, Chang Seong, Bae, Eun Hui, Ma, Seong Kwon, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241134/
https://www.ncbi.nlm.nih.gov/pubmed/35767918
http://dx.doi.org/10.1016/j.redox.2022.102382