Cargando…

Optimal Sacrificial Domains in Mechanical Polyproteins: S. epidermidis Adhesins Are Tuned for Work Dissipation

[Image: see text] The opportunistic pathogen Staphylococcus epidermidis utilizes a multidomain surface adhesin protein to bind host components and adhere to tissues. While it is known that the interaction between the SdrG receptor and its fibrinopeptide target (FgB) is exceptionally mechanostable (∼...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Haipei, Liu, Zhaowei, Yang, Byeongseon, Lopez Morales, Joanan, Nash, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241160/
https://www.ncbi.nlm.nih.gov/pubmed/35783175
http://dx.doi.org/10.1021/jacsau.2c00121