Glioma-associated mesenchymal stem cells-mediated PD-L1 expression is attenuated by Ad5-Ki67/IL-15 in GBM treatment

BACKGROUND: Glioblastoma (GBM) is a highly immunosuppressive and vascular malignant brain tumor. Current therapeutic strategies targeting tumor cells have limited efficacy because of the immunosuppressive microenvironment and vascularization. Glioma-associated mesenchymal stem cells (GA-MSCs) have b...

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Detalles Bibliográficos
Autores principales: Zhang, Qing, Zhang, Junwen, Wang, Peiwen, Zhu, Guidong, Jin, Guishan, Liu, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241198/
https://www.ncbi.nlm.nih.gov/pubmed/35765095
http://dx.doi.org/10.1186/s13287-022-02968-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241198/
https://www.ncbi.nlm.nih.gov/pubmed/35765095
http://dx.doi.org/10.1186/s13287-022-02968-z

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