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Glioma-associated mesenchymal stem cells-mediated PD-L1 expression is attenuated by Ad5-Ki67/IL-15 in GBM treatment
BACKGROUND: Glioblastoma (GBM) is a highly immunosuppressive and vascular malignant brain tumor. Current therapeutic strategies targeting tumor cells have limited efficacy because of the immunosuppressive microenvironment and vascularization. Glioma-associated mesenchymal stem cells (GA-MSCs) have b...
Autores principales: | Zhang, Qing, Zhang, Junwen, Wang, Peiwen, Zhu, Guidong, Jin, Guishan, Liu, Fusheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241198/ https://www.ncbi.nlm.nih.gov/pubmed/35765095 http://dx.doi.org/10.1186/s13287-022-02968-z |
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