CX3CR1 deficiency aggravates amyloid driven neuronal pathology and cognitive decline in Alzheimer’s disease

BACKGROUND: Despite its identification as a key checkpoint regulator of microglial activation in Alzheimer’s disease, the overarching role of CX3CR1 signaling in modulating mechanisms of Aβ driven neurodegeneration, including accumulation of hyperphosphorylated tau is not well understood. METHODOLOG...

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Detalles Bibliográficos
Autores principales: Puntambekar, Shweta S., Moutinho, Miguel, Lin, Peter Bor-Chian, Jadhav, Vaishnavi, Tumbleson-Brink, Danika, Balaji, Ananya, Benito, Martin Alvarado, Xu, Guixiang, Oblak, Adrian, Lasagna-Reeves, Cristian A., Landreth, Gary E., Lamb, Bruce T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241248/
https://www.ncbi.nlm.nih.gov/pubmed/35764973
http://dx.doi.org/10.1186/s13024-022-00545-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241248/
https://www.ncbi.nlm.nih.gov/pubmed/35764973
http://dx.doi.org/10.1186/s13024-022-00545-9

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