The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition

BACKGROUND: The activation of the unfolded protein response (UPR) is closely linked to the pathogenesis of renal injuries. However, the role of XBP1, a crucial regulator of adaptive UPR, remains unclear during the transition from acute kidney injury (AKI) to chronic kidney disease (CKD). METHODS: We...

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Detalles Bibliográficos
Autores principales: Chen, Jia-Huang, Wu, Chia-Hsien, Jheng, Jia-Rong, Chao, Chia-Ter, Huang, Jenq-Wen, Hung, Kuan-Yu, Liu, Shing-Hwa, Chiang, Chih-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241279/
https://www.ncbi.nlm.nih.gov/pubmed/35765067
http://dx.doi.org/10.1186/s12929-022-00828-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241279/
https://www.ncbi.nlm.nih.gov/pubmed/35765067
http://dx.doi.org/10.1186/s12929-022-00828-9

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