Hypoxia drives hematopoiesis with the enhancement of T lineage through eliciting arterial specification of hematopoietic endothelial progenitors from hESC

BACKGROUND: Hematopoietic stem cells are able to self-renew and differentiate into all blood cell lineages. Hematopoietic stem cell transplantation is a mainstay of life-saving therapy for hematopoietic malignancies and hypoproliferative disorders. In vitro hematopoietic differentiation of human plu...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Chen, Chuxin, Cheng, Yang, Fu, Yingjie, Zhong, Zhiyong, Yang, Yu, Lv, Ling, Chen, Honglin, Huang, Jian, Duan, Yuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241298/
https://www.ncbi.nlm.nih.gov/pubmed/35765115
http://dx.doi.org/10.1186/s13287-022-02967-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241298/
https://www.ncbi.nlm.nih.gov/pubmed/35765115
http://dx.doi.org/10.1186/s13287-022-02967-0

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