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Lamotrigine protects against cognitive deficits, synapse and nerve cell damage, and hallmark neuropathologies in a mouse model of Alzheimer’s disease

Lamotrigine (LTG) is a widely used drug for the treatment of epilepsy. Emerging clinical evidence suggests that LTG may improve cognitive function in patients with Alzheimer’s disease. However, the underlying molecular mechanisms remain unclear. In this study, amyloid precursor protein/presenilin 1...

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Detalles Bibliográficos
Autores principales: Fu, Xin-Xin, Duan, Rui, Wang, Si-Yu, Zhang, Qiao-Quan, Wei, Bin, Huang, Ting, Gong, Peng-Yu, Yan, E, Jiang, Teng, Zhang, Ying-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241401/
https://www.ncbi.nlm.nih.gov/pubmed/35799541
http://dx.doi.org/10.4103/1673-5374.343888