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Evolutionary Significance of Fungal Hypermutators: Lessons Learned from Clinical Strains and Implications for Fungal Plant Pathogens

Rapid evolution of fungal pathogens poses a serious threat to medicine and agriculture. The mutation rate determines the pace of evolution of a fungal pathogen. Hypermutator fungal strains have an elevated mutation rate owing to certain defects such as those in the DNA mismatch repair system. Studie...

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Detalles Bibliográficos
Autores principales: Gambhir, Nikita, Harris, Steven D., Everhart, Sydney E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241500/
https://www.ncbi.nlm.nih.gov/pubmed/35638358
http://dx.doi.org/10.1128/msphere.00087-22