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Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans
The CCAAT-binding heme activator protein (HAP) complex, comprising the DNA-binding heterotrimeric complex Hap2/3/5 and transcriptional activation subunit HapX, is a key regulator of iron homeostasis, mitochondrial functions, and pathogenicity in Cryptococcus neoformans, which causes fatal meningoenc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241503/ https://www.ncbi.nlm.nih.gov/pubmed/35638350 http://dx.doi.org/10.1128/msphere.00170-22 |