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Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans

The CCAAT-binding heme activator protein (HAP) complex, comprising the DNA-binding heterotrimeric complex Hap2/3/5 and transcriptional activation subunit HapX, is a key regulator of iron homeostasis, mitochondrial functions, and pathogenicity in Cryptococcus neoformans, which causes fatal meningoenc...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Young, Bahn, Yong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241503/
https://www.ncbi.nlm.nih.gov/pubmed/35638350
http://dx.doi.org/10.1128/msphere.00170-22