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Neutralizing Staphylococcus aureus Virulence with AZD6389, a Three mAb Combination, Accelerates Closure of a Diabetic Polymicrobial Wound

Nonhealing diabetic foot ulcers (DFU), a major complication of diabetes, are associated with high morbidity and mortality despite current standard of care. Since Staphylococcus aureus is the most common pathogen isolated from nonhealing and infected DFU, we hypothesized that S. aureus virulence fact...

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Detalles Bibliográficos
Autores principales: Tkaczyk, Christine, Jones-Nelson, Omari, Shi, Yue Yue, Tabor, David E., Cheng, Lily, Zhang, Tianhui, Sellman, Bret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241520/
https://www.ncbi.nlm.nih.gov/pubmed/35642538
http://dx.doi.org/10.1128/msphere.00130-22