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Generation and Characterization of Human-Mouse STING Chimeras That Allow DENV Replication in Mouse Cells

Our group was the first to describe direct antagonism of the cyclic GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) pathway by dengue virus (DENV) in human cells, and here, we report new findings on the characterization of the interaction between the DENV nonstructural protein 2B (NS2...

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Detalles Bibliográficos
Autores principales: Zhu, Tongtong, Webb, Laurence G., Veloz, Jeury, Wilkins, Maris, Aguirre, Sebastian, Fernandez-Sesma, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241525/
https://www.ncbi.nlm.nih.gov/pubmed/35477320
http://dx.doi.org/10.1128/msphere.00914-21