Cargando…

FKS1 Is Required for Cryptococcus neoformans Fitness In Vivo: Application of Copper-Regulated Gene Expression to Mouse Models of Cryptococcosis

There is an urgent need for new antifungals to treat cryptococcal meningoencephalitis, a leading cause of mortality in people living with HIV/AIDS. An important aspect of antifungal drug development is the validation of targets to determine whether they are required for the survival of the organism...

Descripción completa

Detalles Bibliográficos
Autores principales: Beattie, Sarah R., Jezewski, Andrew J., Ristow, Laura C., Wellington, Melanie, Krysan, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241531/
https://www.ncbi.nlm.nih.gov/pubmed/35506343
http://dx.doi.org/10.1128/msphere.00163-22