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FKS1 Is Required for Cryptococcus neoformans Fitness In Vivo: Application of Copper-Regulated Gene Expression to Mouse Models of Cryptococcosis
There is an urgent need for new antifungals to treat cryptococcal meningoencephalitis, a leading cause of mortality in people living with HIV/AIDS. An important aspect of antifungal drug development is the validation of targets to determine whether they are required for the survival of the organism...
Autores principales: | Beattie, Sarah R., Jezewski, Andrew J., Ristow, Laura C., Wellington, Melanie, Krysan, Damian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241531/ https://www.ncbi.nlm.nih.gov/pubmed/35506343 http://dx.doi.org/10.1128/msphere.00163-22 |
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