High-Throughput Chemical Screen Identifies a 2,5-Disubstituted Pyridine as an Inhibitor of Candida albicans Erg11

Fungal infections contribute to over 1.5 million deaths annually, with Candida albicans representing one of the most concerning human fungal pathogens. While normally commensal in nature, compromise of host immunity can result in C. albicans disseminating into the human bloodstream, causing infectio...

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Detalles Bibliográficos
Autores principales: Du Bois, Antonia C., Xue, Alice, Pham, Chester, Revie, Nicole M., Meyer, Kirsten J., Yashiroda, Yoko, Boone, Charles, Nodwell, Justin R., Stogios, Peter, Savchenko, Alexei, Robbins, Nicole, Iyer, Kali R., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241532/
https://www.ncbi.nlm.nih.gov/pubmed/35531664
http://dx.doi.org/10.1128/msphere.00075-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241532/
https://www.ncbi.nlm.nih.gov/pubmed/35531664
http://dx.doi.org/10.1128/msphere.00075-22

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