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Standard Selection Treatments with Sulfadiazine Limit Plasmodium yoelii Host-to-Vector Transmission

Some antimalarial drugs that have lost clinical usefulness have been repurposed for experimental applications. One example is sulfadiazine, an analog of p-aminobenzoic acid (pABA), which inhibits the parasite’s folate synthesis pathway to block DNA synthesis. Sulfadiazine treatment of mice infected...

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Detalles Bibliográficos
Autores principales: Rios, Kelly T., Dickson, Taylor M., Lindner, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241536/
https://www.ncbi.nlm.nih.gov/pubmed/35586987
http://dx.doi.org/10.1128/msphere.00106-22