Loss of β-Ketoacyl Acyl Carrier Protein Synthase III Activity Restores Multidrug-Resistant Escherichia coli Sensitivity to Previously Ineffective Antibiotics

Antibiotic resistance is one of the most prominent threats to modern medicine. In the latest World Health Organization list of bacterial pathogens that urgently require new antibiotics, 9 out of 12 are Gram-negative, with four being of “critical priority.” One crucial barrier restricting antibiotic...

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Detalles Bibliográficos
Autores principales: Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E., Totsika, Makrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241538/
https://www.ncbi.nlm.nih.gov/pubmed/35574679
http://dx.doi.org/10.1128/msphere.00117-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241538/
https://www.ncbi.nlm.nih.gov/pubmed/35574679
http://dx.doi.org/10.1128/msphere.00117-22

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