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Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance Mechanisms

Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health concern. In this study, we conducted a whole-genome-based molecular characterization to correlate resistance patterns and β-lactamases with C/T resistance among multi-drug resistant P. aeruginosa clinical isolates. Resi...

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Detalles Bibliográficos
Autores principales: Bitar, Ibrahim, Salloum, Tamara, Merhi, Georgi, Hrabak, Jaroslav, Araj, George F., Tokajian, Sima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241553/
https://www.ncbi.nlm.nih.gov/pubmed/35782142
http://dx.doi.org/10.3389/fcimb.2022.922976