Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine

Influenza A viruses (IAV) remain emerging threats to human public health. Live-attenuated influenza vaccines (LAIV) are one of the most effective prophylactic options to prevent disease caused by influenza infections. However, licensed LAIV remain restricted for use in 2- to 49-year-old healthy and...

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Detalles Bibliográficos
Autores principales: Nogales, Aitor, Steel, John, Liu, Wen-Chun, Lowen, Anice C., Rodriguez, Laura, Chiem, Kevin, Cox, Andrew, García-Sastre, Adolfo, Albrecht, Randy A., Dewhurst, Stephen, Martínez-Sobrido, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241597/
https://www.ncbi.nlm.nih.gov/pubmed/35583364
http://dx.doi.org/10.1128/spectrum.00078-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241597/
https://www.ncbi.nlm.nih.gov/pubmed/35583364
http://dx.doi.org/10.1128/spectrum.00078-22

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