Chemical Exploration of a Highly Selective Scaffold with Activity against Intracellular Mycobacterium tuberculosis

We previously identified a phenylthiourea series with activity against intracellular Mycobacterium tuberculosis using a high-throughput, high-content assay. We conducted a catalog structure-activity relationship study with a collection of 35 analogs. We identified several thiourea derivatives with e...

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Detalles Bibliográficos
Autores principales: Njikan, Samuel, Ahmed, Sara, Manning, Alyssa, Awasthi, Divya, Ovechkina, Yulia, Chowdhury, Sultan, Butts, Arielle, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241686/
https://www.ncbi.nlm.nih.gov/pubmed/35612308
http://dx.doi.org/10.1128/spectrum.01161-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241686/
https://www.ncbi.nlm.nih.gov/pubmed/35612308
http://dx.doi.org/10.1128/spectrum.01161-22

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