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Evaluating Mono- and Combination Therapy of Meropenem and Amikacin against Pseudomonas aeruginosa Bacteremia in the Hollow-Fiber Infection Model

Debate continues as to the role of combination antibiotic therapy for the management of Pseudomonas aeruginosa infections. We studied the extent of bacterial killing by and the emergence of resistance to meropenem and amikacin as monotherapies and as a combination therapy against susceptible and res...

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Detalles Bibliográficos
Autores principales: Avent, Minyon L., McCarthy, Kate L., Sime, Fekade B., Naicker, Saiyuri, Heffernan, Aaron J., Wallis, Steven C., Paterson, David L., Roberts, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241727/
https://www.ncbi.nlm.nih.gov/pubmed/35442072
http://dx.doi.org/10.1128/spectrum.00525-22