Screening of the Pandemic Response Box Reveals an Association between Antifungal Effects of MMV1593537 and the Cell Wall of Cryptococcus neoformans, Cryptococcus deuterogattii, and Candida auris

There is an urgent unmet need for novel antifungals. In this study, we searched for novel antifungal activities in the Pandemic Response Box, a collection of 400 structurally diverse compounds in various phases of drug discovery. We identified five molecules which could control the growth of Cryptoc...

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Detalles Bibliográficos
Autores principales: de Oliveira, Haroldo C., Castelli, Rafael F., Reis, Flavia C. G., Samby, Kirandeep, Nosanchuk, Joshua D., Alves, Lysangela R., Rodrigues, Marcio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241760/
https://www.ncbi.nlm.nih.gov/pubmed/35471056
http://dx.doi.org/10.1128/spectrum.00601-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241760/
https://www.ncbi.nlm.nih.gov/pubmed/35471056
http://dx.doi.org/10.1128/spectrum.00601-22

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