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Small, Cationic Antifungal Proteins from Filamentous Fungi Inhibit Candida albicans Growth in 3D Skin Infection Models

The emerging resistance of human-pathogenic fungi to antifungal drugs urges the development of alternative therapeutic strategies. The small, cationic antifungal proteins (AFPs) from filamentous ascomycetes represent promising candidates for next-generation antifungals. These bio-molecules need to b...

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Detalles Bibliográficos
Autores principales: Holzknecht, Jeanett, Dubrac, Sandrine, Hedtrich, Sarah, Galgóczy, László, Marx, Florentine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241769/
https://www.ncbi.nlm.nih.gov/pubmed/35499318
http://dx.doi.org/10.1128/spectrum.00299-22