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Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus

Aspergillus fumigatus is one of the deadliest fungal species, causing hundreds of thousands of deaths each year. Because azoles provide the preferred first-line option for treatment of aspergillosis, the increase in rates of resistance and the poor therapeutic outcomes for patients infected with a r...

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Detalles Bibliográficos
Autores principales: Kühbacher, Alexander, Peiffer, Mandy, Hortschansky, Peter, Merschak, Petra, Bromley, Michael J., Haas, Hubertus, Brakhage, Axel A., Gsaller, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241776/
https://www.ncbi.nlm.nih.gov/pubmed/35575535
http://dx.doi.org/10.1128/spectrum.01209-22