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Histone Acetylation Regulator Gcn5 Mediates Drug Resistance and Virulence of Candida glabrata

Candida glabrata is poised to adapt to drug pressure rapidly and acquire antifungal resistance leading to therapeutic failure. Given the limited antifungal armamentarium, there is an unmet need to explore new targets or therapeutic strategies for antifungal treatment. The lysine acetyltransferase Gc...

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Detalles Bibliográficos
Autores principales: Yu, Shuying, Paderu, Padmaja, Lee, Annie, Eirekat, Sami, Healey, Kelley, Chen, Liang, Perlin, David S., Zhao, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241792/
https://www.ncbi.nlm.nih.gov/pubmed/35658596
http://dx.doi.org/10.1128/spectrum.00963-22