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No Genus-Specific Gene Is Essential for the Replication of Fowl Adenovirus 4 in Chicken LMH Cells

Essential genus-specific genes have not been discovered for fowl adenovirus (FAdV), which hampers the development of FAdV-based vectors and attenuated FAdV vaccines. Reverse genetics approaches were employed to construct FAdV-4 mutants carrying deletions or frameshift mutations covering the whole le...

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Detalles Bibliográficos
Autores principales: Liu, Xinglong, Zou, Xiaohui, Zhang, Wenfeng, Guo, Xiaojuan, Wang, Min, Lv, Yingtao, Hung, Tao, Lu, Zhuozhuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241798/
https://www.ncbi.nlm.nih.gov/pubmed/35638786
http://dx.doi.org/10.1128/spectrum.00470-22