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Caspofungin Cerebral Penetration and Therapeutic Efficacy in Experimental Cerebral Aspergillosis

Despite best available therapy, cerebral aspergillosis is an often-lethal complication of disseminated aspergillosis. There is an urgent need to expand the currently limited therapeutic options. In this study, we assessed cerebral drug exposure and efficacy of caspofungin (CAS) using a lethal infant...

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Detalles Bibliográficos
Autores principales: Ullmann, Irina, Aregger, Andrea, Leib, Stephen L., Zimmerli, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241807/
https://www.ncbi.nlm.nih.gov/pubmed/35435756
http://dx.doi.org/10.1128/spectrum.02753-21