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Caspofungin Cerebral Penetration and Therapeutic Efficacy in Experimental Cerebral Aspergillosis
Despite best available therapy, cerebral aspergillosis is an often-lethal complication of disseminated aspergillosis. There is an urgent need to expand the currently limited therapeutic options. In this study, we assessed cerebral drug exposure and efficacy of caspofungin (CAS) using a lethal infant...
Autores principales: | Ullmann, Irina, Aregger, Andrea, Leib, Stephen L., Zimmerli, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241807/ https://www.ncbi.nlm.nih.gov/pubmed/35435756 http://dx.doi.org/10.1128/spectrum.02753-21 |
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