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A Critical Role for p53 during the HPV16 Life Cycle

Human papillomaviruses (HPV) are causative agents in ano-genital and oral cancers; HPV16 is the most prevalent type detected in human cancers. The HPV16 E6 protein targets p53 for proteasomal degradation to facilitate proliferation of the HPV16 infected cell. However, in HPV16 immortalized cells E6...

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Detalles Bibliográficos
Autores principales: Fontan, Christian T., James, Claire D., Prabhakar, Apurva T., Bristol, Molly L., Otoa, Raymonde, Wang, Xu, Karimi, Elmira, Rajagopalan, Pavithra, Basu, Devraj, Morgan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241828/
https://www.ncbi.nlm.nih.gov/pubmed/35608342
http://dx.doi.org/10.1128/spectrum.00681-22