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A Critical Role for p53 during the HPV16 Life Cycle
Human papillomaviruses (HPV) are causative agents in ano-genital and oral cancers; HPV16 is the most prevalent type detected in human cancers. The HPV16 E6 protein targets p53 for proteasomal degradation to facilitate proliferation of the HPV16 infected cell. However, in HPV16 immortalized cells E6...
Autores principales: | Fontan, Christian T., James, Claire D., Prabhakar, Apurva T., Bristol, Molly L., Otoa, Raymonde, Wang, Xu, Karimi, Elmira, Rajagopalan, Pavithra, Basu, Devraj, Morgan, Iain M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241828/ https://www.ncbi.nlm.nih.gov/pubmed/35608342 http://dx.doi.org/10.1128/spectrum.00681-22 |
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