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Gut Microbiota Mediates the Therapeutic Effect of Monoclonal Anti-TLR4 Antibody on Acetaminophen-Induced Acute Liver Injury in Mice

Acetaminophen (APAP) overdose is one of the most common causes of acute liver injury (ALI) in Western countries. Many studies show that the gut microbiota plays an important role in liver injury. Currently, the only approved treatment for APAP-induced ALI is N-acetylcysteine; therefore, it is essent...

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Detalles Bibliográficos
Autores principales: Sun, Xuewei, Cui, Qian, Ni, Juan, Liu, Xiaoguang, Zhu, Jin, Zhou, Tingting, Huang, HuaYing, OuYang, Ke, Wu, Yulong, Yang, Zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241835/
https://www.ncbi.nlm.nih.gov/pubmed/35536057
http://dx.doi.org/10.1128/spectrum.00647-22