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LMP1 Induces p53 Protein Expression via the H19/miR-675-5p Axis

Epstein-Barr virus (EBV), a ubiquitous oncogenic herpesvirus, infects more than 90% of the adult population worldwide. The long noncoding RNA H19 is downregulated in EBV-positive gastric cancer (EBVaGC) and nasopharyngeal cancer (NPC). In this study, we found that loss of H19 is caused by hypermethy...

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Detalles Bibliográficos
Autores principales: Li, Jun, Zhang, Yan, Sun, Lingling, Liu, Song, Zhao, Menghe, Luo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241841/
https://www.ncbi.nlm.nih.gov/pubmed/35674441
http://dx.doi.org/10.1128/spectrum.00006-22