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Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis

Individuals co-infected with HIV and Mycobacterium tuberculosis (Mtb) are more likely to develop severe tuberculosis (TB) disease than HIV-naive individuals. To understand how a chronic pre-existing Simian immunodeficiency virus (SIV) infection impairs the early immune response to Mtb, we used the M...

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Detalles Bibliográficos
Autores principales: Moriarty, Ryan V., Rodgers, Mark A., Ellis, Amy L., Balgeman, Alexis J., Larson, Erica C., Hopkins, Forrest, Chase, Michael R., Maiello, Pauline, Fortune, Sarah M., Scanga, Charles A., O’Connor, Shelby L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241861/
https://www.ncbi.nlm.nih.gov/pubmed/35467372
http://dx.doi.org/10.1128/spectrum.01724-21