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Spontaneous Control of SIV Replication Does Not Prevent T Cell Dysregulation and Bacterial Dissemination in Animals Co-Infected with M. tuberculosis
Individuals co-infected with HIV and Mycobacterium tuberculosis (Mtb) are more likely to develop severe tuberculosis (TB) disease than HIV-naive individuals. To understand how a chronic pre-existing Simian immunodeficiency virus (SIV) infection impairs the early immune response to Mtb, we used the M...
Autores principales: | Moriarty, Ryan V., Rodgers, Mark A., Ellis, Amy L., Balgeman, Alexis J., Larson, Erica C., Hopkins, Forrest, Chase, Michael R., Maiello, Pauline, Fortune, Sarah M., Scanga, Charles A., O’Connor, Shelby L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241861/ https://www.ncbi.nlm.nih.gov/pubmed/35467372 http://dx.doi.org/10.1128/spectrum.01724-21 |
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