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Vaccinia Virus Attenuation by Codon Deoptimization of the A24R Gene for Vaccine Development
Poxviruses have large DNA genomes, and they are able to infect multiple vertebrate and invertebrate animals, including humans. Despite the eradication of smallpox, poxvirus infections still remain a significant public health concern. Vaccinia virus (VV) is the prototypic member in the poxviridae fam...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241885/ https://www.ncbi.nlm.nih.gov/pubmed/35583360 http://dx.doi.org/10.1128/spectrum.00272-22 |