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Comparison of Ceftolozane/Tazobactam Infusion Regimens in a Hollow-Fiber Infection Model against Extensively Drug-Resistant Pseudomonas aeruginosa Isolates

The aim of this study was to compare the efficacy of intermittent (1-h), extended (4-h), and continuous ceftolozane-tazobactam (C/T) infusion against three extensively drug-resistant (XDR) sequence type (ST) 175 P. aeruginosa isolates with different susceptibilities to C/T (MIC = 2 to 16 mg/L) in a...

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Detalles Bibliográficos
Autores principales: Montero, María Milagro, Domene-Ochoa, Sandra, López-Causapé, Carla, López-Montesinos, Inmaculada, Luque, Sonia, Sorlí, Luisa, Campillo, Núria, Padilla, Eduardo, Prim, Núria, Ferrer Alapont, Lorena, Grau, Santiago, Oliver, Antonio, Horcajada, Juan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241897/
https://www.ncbi.nlm.nih.gov/pubmed/35695526
http://dx.doi.org/10.1128/spectrum.00892-22