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Development of an Efficient C-to-T Base-Editing System and Its Application to Cellulase Transcription Factor Precise Engineering in Thermophilic Fungus Myceliophthora thermophila

Myceliophthora thermophila is a thermophilic fungus with great potential in biorefineries and biotechnology. The base editor is an upgraded version of the clustered regularly interspaced short palindromic repeats (CRISPR)-dependent genome-editing tool that introduces precise point mutations without...

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Detalles Bibliográficos
Autores principales: Zhang, Chenyang, Li, Nan, Rao, Lang, Li, Jingen, Liu, Qian, Tian, Chaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241923/
https://www.ncbi.nlm.nih.gov/pubmed/35608343
http://dx.doi.org/10.1128/spectrum.02321-21