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DWV 3C Protease Uncovers the Diverse Catalytic Triad in Insect RNA Viruses

Deformed wing virus (DWV) is the most prevalent Iflavirus that is infecting honey bees worldwide. However, the mechanisms of its infection and replication in host cells are poorly understood. In this study, we analyzed the structure and function of DWV 3C protease (3C(pro)), which is necessary for t...

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Detalles Bibliográficos
Autores principales: Yuan, Xuye, Kadowaki, Tatsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241925/
https://www.ncbi.nlm.nih.gov/pubmed/35575593
http://dx.doi.org/10.1128/spectrum.00068-22