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Synergistic Antimicrobial Effect of Colistin in Combination with Econazole against Multidrug-Resistant Acinetobacter baumannii and Its Persisters

Colistin is a last-line antibiotic which acts by causing membrane permeabilization in Gram-negative bacteria. However, its clinical value has been limited by its toxicity and the emergence of resistant organisms. In this study, we showed that econazole and colistin can act synergistically to produce...

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Detalles Bibliográficos
Autores principales: Xie, Miaomiao, Chen, Kaichao, Chan, Edward Wai-Chi, Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241926/
https://www.ncbi.nlm.nih.gov/pubmed/35467374
http://dx.doi.org/10.1128/spectrum.00937-22