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Yersinia pestis-Induced Mitophagy That Balances Mitochondrial Homeostasis and mROS-Mediated Bactericidal Activity

Manipulating mitochondrial homeostasis is essential for host defense against infection and pathogen survival in cells. This study reports for the first time that Y. pestis infection caused mitochondria damage that subsequently leads to the activation of Pink1/Parkin-independent mitophagy in macropha...

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Detalles Bibliográficos
Autores principales: Jiao, Yang, Cao, Shiyang, Zhang, Yuan, Tan, Yafang, Zhou, Yazhou, Wang, Tong, You, Yang, Chen, Hongyan, Ren, Yifan, Yang, Ruifu, Du, Zongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241946/
https://www.ncbi.nlm.nih.gov/pubmed/35768946
http://dx.doi.org/10.1128/spectrum.00718-22