Cargando…

Systematic synthesis of bisected N-glycans and unique recognitions by glycan-binding proteins

Bisected N-glycans represent a unique class of protein N-glycans that play critical roles in many biological processes. Herein, we describe the systematic synthesis of these structures. A bisected N-glycan hexasaccharide was chemically assembled with two orthogonal protecting groups attached at the...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Xuefeng, Wang, Shuaishuai, Gadi, Madhusudhan Reddy, Liu, Ding, Wang, Peng G., Wan, Xiu-Feng, Zhang, Jian, Chen, Xi, Pepi, Lauren E., Azadi, Parastoo, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9241959/
https://www.ncbi.nlm.nih.gov/pubmed/35872821
http://dx.doi.org/10.1039/d1sc05435j