Paradoxical prolongation of QT interval during exercise in patients with hypertrophic cardiomyopathy: cellular mechanisms and implications for diastolic function

AIMS: Ventricular cardiomyocytes from hypertrophic cardiomyopathy (HCM) patient hearts show prolonged action potential duration (APD), impaired intracellular Ca(2+) homeostasis and abnormal electrical response to beta -adrenergic stimulation. We sought to determine whether this behaviour is associat...

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Detalles Bibliográficos
Autores principales: Coppini, Raffaele, Beltrami, Matteo, Doste, Ruben, Bueno-Orovio, Alfonso, Ferrantini, Cecilia, Vitale, Giulia, Pioner, Josè Manuel, Santini, Lorenzo, Argirò, Alessia, Berteotti, Martina, Mori, Fabio, Marchionni, Niccolò, Stefàno, Pierluigi, Cerbai, Elisabetta, Poggesi, Corrado, Olivotto, Iacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242073/
https://www.ncbi.nlm.nih.gov/pubmed/35919344
http://dx.doi.org/10.1093/ehjopen/oeac034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242073/
https://www.ncbi.nlm.nih.gov/pubmed/35919344
http://dx.doi.org/10.1093/ehjopen/oeac034

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