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ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

The ParABS system is essential for prokaryotic chromosome segregation. After loading at parS on the genome, ParB (partition protein B) proteins rapidly redistribute to distances of ~15 kilobases from the loading site. It has remained puzzling how this large-distance spreading can occur along DNA loa...

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Detalles Bibliográficos
Autores principales: Tišma, Miloš, Panoukidou, Maria, Antar, Hammam, Soh, Young-Min, Barth, Roman, Pradhan, Biswajit, Barth, Anders, van der Torre, Jaco, Michieletto, Davide, Gruber, Stephan, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242446/
https://www.ncbi.nlm.nih.gov/pubmed/35767606
http://dx.doi.org/10.1126/sciadv.abn3299