Suppression of osteoclast multinucleation via a posttranscriptional regulation–based spatiotemporally selective delivery system

Redundancy of multinucleated mature osteoclasts, which results from the excessive fusion of mononucleated preosteoclasts (pOCs), leads to osteolytic diseases such as osteoporosis. Unfortunately, the currently available clinical drugs completely inhibit osteoclasts, thus interfering with normal physi...

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Detalles Bibliográficos
Autores principales: Wang, Qingqing, Wang, Haoli, Yan, Huige, Tian, Hongsen, Wang, Yining, Yu, Wei, Dai, Zhanqiu, Chen, Pengfei, Liu, Zhaoming, Tang, Ruikang, Jiang, Chao, Fan, Shunwu, Liu, Xin, Lin, Xianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242458/
https://www.ncbi.nlm.nih.gov/pubmed/35767605
http://dx.doi.org/10.1126/sciadv.abn3333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242458/
https://www.ncbi.nlm.nih.gov/pubmed/35767605
http://dx.doi.org/10.1126/sciadv.abn3333

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