Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H(+)-ATPase

Weibel-Palade bodies (WPB) are unique secretory granules of endothelial cells that store the procoagulant von-Willebrand factor (VWF) in a highly compacted form. Upon exocytosis the densely packed VWF unfurls into long strands that expose binding sites for circulating platelets and thereby initiate...

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Detalles Bibliográficos
Autores principales: Terglane, Julian, Menche, Dirk, Gerke, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242466/
https://www.ncbi.nlm.nih.gov/pubmed/35767558
http://dx.doi.org/10.1371/journal.pone.0270299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242466/
https://www.ncbi.nlm.nih.gov/pubmed/35767558
http://dx.doi.org/10.1371/journal.pone.0270299

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