EPIC: Inferring relevant cell types for complex traits by integrating genome-wide association studies and single-cell RNA sequencing

More than a decade of genome-wide association studies (GWASs) have identified genetic risk variants that are significantly associated with complex traits. Emerging evidence suggests that the function of trait-associated variants likely acts in a tissue- or cell-type-specific fashion. Yet, it remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Rujin, Lin, Dan-Yu, Jiang, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242467/
https://www.ncbi.nlm.nih.gov/pubmed/35709291
http://dx.doi.org/10.1371/journal.pgen.1010251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9242467/
https://www.ncbi.nlm.nih.gov/pubmed/35709291
http://dx.doi.org/10.1371/journal.pgen.1010251

Ejemplares similares